The effect of probiotic supplementation on lipid profile and arylesterase activity of paraoxonase enzyme in women with rheumatoid arthritis

Research Vice chancellor, Tabriz University of Medical Sciences0 个研究点目标入组 60 人开始时间: 待定最近更新: 2018年2月22日

适应症

试验速览

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•patients diagnosed with rheumatoid arthritis, based on ACR criteria; having inactive to moderate rheumatoid arthritis; under treatment with DMARDs (Methotrexate, Hydroxychloroquine and Prednisolone less than 10 milligrams per day) and not receiving NSAIDs or cytokine inhibitors; stable medication for at least 3 month prior to the interventions; having body mass index (BMI) less than 40; willing to participate in the study; ages between 20 and 80. Exclusion criteria: pregnant and lactating women; hormone therapy or receiving oral contraceptives; having diabetes mellitus, thyroid disorders, kidney or hepatic diseases or Cushing's syndrome; having inflammatory bowel disease or other inflammatory disorders; having digestive tract disorders or lactose intolerance; Taking antioxidant, vitamin, fiber or omega-3 supplements 3 weeks prior to the interventions; using antibiotics a month prior to the interventions; being on a weight reduction diet; smoking or being exposed to cigarette smoke; using other probiotic products.

发起方

Research Vice chancellor, Tabriz University of Medical Sciences