Quality Measurement and Improvement Study of Surgical Coronary Revascularization: Secondary Prevention
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 10,009
- 试验地点
- 1
- 主要终点
- statins use at discharge
研究概览
简要总结
The investigators have identified underuse of secondary prevention medications at discharge of patients underwent coronary artery bypass grafting (CABG) in China. The aim of this study is to develop series of quality improvement strategies focusing on secondary prevention medications for patients underwent CABG, and to evaluate their effectiveness and safety via a hospital-level cluster randomized clinical trial. The investigators established a network of 60 hospitals which have participated into Chinese Cardiovascular Surgery Registry and submitted 50 or more CABG surgeries already. The participating sites will be divided into intervention and control groups in a 1:1 ratio. The intervention group will undertake intervention of quality improvement strategies, while the control group will maintain the routine practice pattern. All hospitals will consecutively enroll and submit data of CABG during the enrollment period, estimated for 6 months. The prescribing rates of angiotensin converting enzyme inhibitor (ACEI), angiotensin receptor blocker (ARB), beta-blockers, statins and aspirins will be compared between 2 groups.
详细描述
The investigators have identified underuse of secondary prevention medications at discharge of patients underwent coronary artery bypass grafting (CABG) in China. The aim of this study is to develop series of quality improvement strategies focusing on secondary prevention medications for patients underwent CABG, and to evaluate their effectiveness and safety via a hospital-level cluster randomized clinical trial. The investigators established a network of 60 hospitals which have participated into Chinese Cardiovascular Surgery Registry and submitted 50 or more CABG surgeries already. The participating sites will be divided into intervention and control groups in a 1:1 ratio. The intervention group will undertake intervention of quality improvement strategies, while the control group will maintain the routine practice pattern. All hospitals will consecutively enroll and submit data of CABG during the enrollment period of estimated 6 months. The prescription rates of ACEI, ARB, beta-blockers, statins and aspirins will be compared between 2 groups.
Before the enrollment period, the investigators have developed series of quality improvement strategies focusing on secondary prevention medications for patients underwent CABG, including training with guidelines of secondary preventions, determining improvement goals with participating sites, intervention tools (workflow posters and cards, checklists to inform the use of secondary prevention medications) and periodical quality feedback reports.
In the enrollment period, participating hospitals will be divided into intervention and control groups in a 1:1 ratio using minimization allocation.
The investigators will collect data on the prescription rates from central medical record abstraction, case report forms submitted by participating sites and checklists submitted by intervention groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- Single (Outcomes Assessor)
盲法说明
Outcomes assessor and data extractors were blind to the results of randomization
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients underwent CABG during the enrollment period in participating sites
排除标准
- •Patients who die during hospitalization
- •Patients who withdrawn from hospital against doctors' recommendations
- •Patients who transfer out to other medical care institutions without discharge prescription
研究组 & 干预措施
Intervention group
The intervention group will take the secondary prevention quality improvement strategies into implementation.
干预措施: Quality improvement strategies (Behavioral)
Control group
The control goup will maintain the routine practice pattern.
结局指标
主要结局
statins use at discharge
时间窗: 14 days on average (during hospitalization)
Proportion of statins prescription at discharge among eligible patients
次要结局
- ACEI/ARBs use at discharge(14 days on average (during hospitalization))
- β-blockers use at discharge(14 days on average (during hospitalization))
- aspirins use at discharge(14 days on average (during hospitalization))
