The Effect of Lipedema on Knee Osteoarthritis: A Cross-Sectional Analysis of Clinical Symptoms and Ultrasonographic Findings
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 76
- 试验地点
- 2
研究概览
简要总结
This study will be one of the few to examine the effect of lipedema on knee osteoarthritis in a comparative manner with a control group within the same osteoarthritis context. Although the relationship between obesity and osteoarthritis has been extensively studied in the literature, the effect of specific adipose tissue pathologies, such as lipedema, on osteoarthritis has not been sufficiently investigated. This study aims to demonstrate the independent effect of lipedema on osteoarthritis, evaluate clinical and ultrasonographic parameters together, and contribute to early diagnosis and targeted rehabilitation strategies.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 30 Years 至 65 Years(Adult, Older Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •All participants (Group 1 + Group 2)
- •Women aged 30-65
- •With a clinical and radiological diagnosis of knee osteoarthritis
- •Who agreed to participate in the study
- •Group 1 (knee osteoarthritis with lipedema):
- •Patients who meet the Wold criteria for a clinical diagnosis of lipedema
- •An increase in subcutaneous fat thickness confirmed by ultrasound
- •Group 2 (knee osteoarthritis without lipedema):
- •No diagnosis of lipedema
- •Exclusion of lymphedema and venous diseases
排除标准
- •Inflammatory arthritis
- •History of knee surgery
- •Intra-articular injection within the past 6 months
- •Acute trauma
- •Systemic connective tissue disease
- •Severe venous insufficiency or lymphedema
- •History of malignancy
- •Use of gabapentinoids/SNRIs/SSRIs due to fibromyalgia or psychiatric illness
- •Severe cognitive impairment or communication problems that would prevent participation in the study
- •Pregnancy
- •Participants who were informed about the study and refused to participate
研究组 & 干预措施
Group 1
Knee osteoarthritis with lipedema
Group 2
Knee osteoarthritis without lipedema
研究者
Kadir Songur
Dr. Lecturer
Izmir Democracy University
