Study of the Colonic Carriage of Staphylococcus Aureus in a Prospective Cohort of Patients Undergoing Endoscopic Screening for Digestive Cancer in the University Hospital of Saint-Etienne.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 112
- 试验地点
- 2
- 主要终点
- Number of patient with Staphylococcus aureus colonic carriage
研究概览
简要总结
Epidemiological study aiming to describe the carriage (nasal, throat, groin, rectal and colonic) of S. aureus in patients without chronic digestive disease who are going to have a colonoscopy for cancer screening. The carriage will be analyzed globally and the similarity of strains isolated from each site will be analyzed using molecular tools. The aim of this study is to better estimate the digestive reservoir of S. aureus to better prevent endogenous infections due to this bacterium.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient affiliated to French social security
- •Written consent of the patient
- •Patient needing a colonoscopy in the University Hospital of Saint-Etienne, France
排除标准
- •Patient who decline to participate to the study
- •Patient in the incapacity to give consent
- •Patient receiving treatment with anticoagulant or antiaggregant platelets
- •Patients with a known haemostatic disorder
- •Pregnant woman
- •Patients with a chronic disease of the gastrointestinal tract
- •Patients receiving long-term corticosteroid
- •Patient receiving anti staphylococcal antibiotics
研究组 & 干预措施
Patients undergoing a colonoscopy
Staphylococcus aureus carriage is measured in nose, throat, colon, rectum and groin
干预措施: Staphylococcus aureus carriage (Other)
结局指标
主要结局
Number of patient with Staphylococcus aureus colonic carriage
时间窗: Day 1
Staphylococcus aureus carriage in the colon is measured by biopsy
次要结局
- Number of patient with Staphylococcus aureus carriage in the nose(Day 1)
- Number of patient with similar Staphylococcus aureus strains in the nose and in the rectum(Day 1)
- Number of patient with Staphylococcus aureus carriage in the throat(Day 1)
- Number of patient with Staphylococcus aureus carriage in the groin(Day 1)