Contrasting Effects of Verbal Treatment and Gesture Plus Verbal Treatment for Word Retrieval in Cantonese Speakers With Aphasia
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Changes in the scores of the Naming Probes
研究概览
简要总结
This research aims to explore the relative efficacy of Verbal-only and GVT on naming difficulty in Cantonese-speaking people with aphasia (PWA).
The primary research question in this study is: "For Cantonese-speaking people with aphasia, what are the relative effects of verbal treatment compared to gesture plus verbal treatment (GVT) on verbal and gesture naming at different levels?"
People with aphasia will be engaged in a repeated measures experimental design. Participants will be engaged in two phases of training. In the first phase, participants will be assigned to receive verbal-only treatment. To minimize and prevent the carry-over effects caused by the first intervention, a one-month washout period will be implemented before the start of the second phase. After a washout period, participants will switch to GVT in the second phase.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Sequential
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosed with aphasia
- •Demonstrate Word finding Difficulty (WFD)
- •Able to repeat single words
- •Normal (or corrected) vision and hearing
- •Aphasia resulting from a unilateral left hemisphere stroke
- •Premorbidly fluent in spoken Cantonese
- •Without significant cognitive impairments
- •Chronic aphasia resulting from a unilateral left hemisphere stroke
排除标准
- •A history of other neurological disorders
- •With the above moderate to severe or severe motor speech impairment
- •With moderate to severe apraxia of speech
- •With very mild or very severe aphasia
研究组 & 干预措施
Verbal-only
This is a within-subject comparison study where each participant receives both interventions sequentially. During the first phase, participants receive verbal-only therapy (VT). In the subsequent phase, they receive Gesture verbal treatment (GVT). The order of interventions is fixed, and each participant acts as their own control to compare the effects of the two interventions.
干预措施: Verbal treatment (Behavioral)
Gesture plus Verbal
This is a within-subject comparison study where each participant receives both interventions sequentially. During the first phase, participants receive verbal-only therapy (VT). In the subsequent phase, they receive Gesture verbal treatment (GVT). The order of interventions is fixed, and each participant acts as their own control to compare the effects of the two interventions.
干预措施: Gesture plus verbal treatment (Behavioral)
结局指标
主要结局
Changes in the scores of the Naming Probes
时间窗: From enrollment to the end of treatment at 4 weeks
The treatment effects on naming will be assessed through verbal naming and gesture production using the black and white drawing naming task. Responses will be counted as correct if they can be identified by the rater as the target word in verbal naming and convey the depicted concept through gesture production, even if the articulation or hand and arm movements are slightly distorted.
次要结局
- Changes in the scores of the Cantonese Aphasia Battery(From enrollment to the end of treatment at 4 weeks)
- Changes in the scores of the Comprehensive Aphasia Test(From enrollment to the end of treatment at 4 weeks)
- Changes in the scores of the Cantonese Boston Naming Test(From enrollment to the end of treatment at 4 weeks)
- Changes in the number of main concepts and gestures in discourse production tasks(From enrollment to the end of treatment at 4 weeks)
- Changes in the scores of the Functional Communication questionnaire(From enrollment to the end of treatment at 4 weeks)
研究者
Annie Zhiyao Hu
Principal Investigator
Hong Kong University