Surgical and Reproductive Results of Fertility-sparing Treatment for Low-grade Endometrial Stromal Sarcoma: A Retrospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- Progression-free survival
研究概览
简要总结
This study is to investigate the survival outcomes and fertility outcomes in patients with uterine low-grade endometrial stromal sarcoma (LGESS) treated in Peking Union Medical College Hospital. All primary and recurrent LGESS patients will be enrolled. The study will collect retrospectively data consisting of epidemiological characteristics, surgical, medical treatment and adjuvant therapy. Details about recurrence, mortality, pregnancy and obstetrical outcomes are also followed as primary endpoints. Fertility-sparing procedures, including uterine-sparing and ovary-sparing surgeries will be recorded specifically.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aged 18 years or older
- •Confirmed of LGESS
- •Acceptance of surgical treatment for LGESS
- •With detailed follow-up outcomes
排除标准
- •Not meeting all of the inclusion criteria
结局指标
主要结局
Progression-free survival
时间窗: One year
Progression-free survival after surgery
Pregnancy rate
时间窗: One year
Pregnancy rate after surgery in patients with fertility-sparing patients
Overall survival
时间窗: One year
Overall survival after surgery
次要结局
- Full-term pregnancy rate(One year)
- Miscarriage rate(One year)
研究者
Lei Li
Professor
Peking Union Medical College Hospital