NCT06650293已完成不适用
Effect of Vitamin D Supplementation as Adjuvant Therapy in Neonatal Jaundice in Combination With Phototherapy
Muhammad Aamir Latif1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2022年5月10日最近更新:
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Total Serum bilirubin levels
研究概览
简要总结
Neonatal jaundice frequently occur during initial week of life. Neonatal jaundice is one of the leading causes of hospital admission and readmission. Some studies have suggested that the healthy newborns with hyperbilirubinemia outside the physiological range have notably reduced serum vitamin D levels. This deficiency is inversely associated with neonatal hyperbilirubinemia, suggesting that low vitamin D levels could be a potential risk factor for jaundice among neonates.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 3 Days 至 28 Days（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Both genders
- •Admitted between 3-28 days of age.
- •Indirect hyperbilirubinemia with TSB levels between 14-20 mg/dL
- •Born via either cesarean or vaginal delivery
- •Birth weight greater than 2500 grams
排除标准
- •Prior phototherapy treatment
- •Preterm birth (gestational age below 37 weeks).
- •SpO2 < 95% at the time of admission
- •Severe respiratory distress or failure
- •Neonatal sepsis
- •Congenital anomalies
- •Parents/guardians unwilling to let their neonates be part of this study.
研究组 & 干预措施
Group-A
Experimental
Neonates receive phototherapy plus vitamin D
干预措施: Vitamin D (Drug)
结局指标
主要结局
Total Serum bilirubin levels
时间窗: 5 days
Total Serum bilirubin levels evaluated
次要结局
未报告次要终点
研究者
Muhammad Aamir Latif
Research Consultant
RESnTEC, Institute of Research
研究点 (1)
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