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临床试验/NCT07582757
NCT07582757已完成不适用

The Proactive and Joint Attention Processing Characteristics of Children With Autism Induced by Social Threat Scenarios

University of Electronic Science and Technology of China1 个研究点 分布在 1 个国家目标入组 56 人开始时间: 2024年12月29日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
56
试验地点
1

研究概览

简要总结

This study set up two experiments using the free viewing video paradigm. By setting up social threat scenarios induced by humans (Experiment 1) and non social threat scenarios induced by objects (Experiment 2), combined with eye tracking and fNIRS technology, we explored the eye movement patterns and related brain activation characteristics of IJA in children with ASD.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
3 Years 至 10 Years(Child)
性别
All
接受健康志愿者

入选标准

  • For ASD group:
  • 3 years ≤ age ≤ 10 years;
  • a diagnosis of autism spectrum disorder based on clinical symptoms, confirmed using the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) and other auxiliary diagnostic scales, including the Autism Diagnostic Interview-Revised (ADI-R) and the Childhood Autism Rating Scale (CARS);
  • further confirmation of ASD symptoms by experimenters with established research reliability using the Autism Diagnostic Observation Schedule, Second Edition (ADOS-2), with severity scores reported;
  • absence of comorbid physical diseases or other psychiatric disorders, including normal vision (or corrected-to-normal vision) and normal hearing;
  • no receipt of medication, transcranial magnetic stimulation (TMS), or transcranial direct current stimulation (tDCS) within the past three months.
  • For TD group:The inclusion criterion for the TD group was a score below the cutoff on the Social Responsiveness Scale (SRS).

排除标准

  • For ASD group:
  • age < 3 years or > 10 years;
  • absence of a diagnosis of autism spectrum disorder based on the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) and other auxiliary diagnostic scales, including the Autism Diagnostic Interview-Revised (ADI-R) and the Childhood Autism Rating Scale (CARS);
  • failure to meet diagnostic criteria after confirmation of ASD symptoms by experimenters with established research reliability using the Autism Diagnostic Observation Schedule, Second Edition (ADOS-2);
  • presence of comorbid physical diseases or other psychiatric disorders, or problems with vision (or corrected-to-normal vision) and hearing;
  • receipt of medication, transcranial magnetic stimulation (TMS), or transcranial direct current stimulation (tDCS) within the past three months.
  • For TD group:
  • children were excluded if their scores on the Social Responsiveness Scale (SRS) exceeded the cutoff.

研究者

发起方
University of Electronic Science and Technology of China
申办方类型
Other
责任方
Principal Investigator
主要研究者

Shan Gao

Professor

University of Electronic Science and Technology of China

研究点 (1)

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