Evaluation of Intrathecal Hyperbaric Bupivacaine With Dexmedetomidine in Adults Undergoing Perianal Surgery
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Duration of analgesia
研究概览
简要总结
The aim of this study is to evaluate the effects of adding 5-mcg dexmedetomidine to hyperbaric bupivacaine in our population as it has never been published before, to enhance the duration of analgesia after perianal procedures requiring spinal saddle block and, thus reducing requirements of postoperative analgesics.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing elective perianal surgery under spinal saddle block were included in the study.
- •Age between 40-80 years
- •ASA status I and II
排除标准
- •Pregnant women
- •Patient with coagulopathy
- •Infection at or near the needle insertion site
- •Allergy to the trial drug
- •Patient with chronic pain
- •Cognitive impairment
- •Patient with known drug or substance abuse
研究组 & 干预措施
Dexemedetomidine
Experimental group received intrathecal dexmedetomidine 5 microgram added to 5 mg of 0.5% hyperbaric bupivacaine in dextrose injection
干预措施: Dexmedetomidine (Drug)
Hyperbaric bupivacaine
Active comparator had 5 mg of 0.5% hyperbaric bupivacaine in dextrose injection alone
干预措施: Hyperbaric bupivacaine % 0.5 (Drug)
结局指标
主要结局
Duration of analgesia
时间窗: 0 hour to 4 hours
duration of analgesia was assessed from induction of anesthesia till patient discharge
次要结局
- Pain score(Two hours post surgery till 24 hours)
研究者
Fahad Ali Tunio
Principal Investigator
Liaquat National Hospital & Medical College