Identification of fibrosis-promoting factors using magnetic resonance elastography (MRE) and proton density fat fraction (PDFF) in nonalcoholic fatty liver disease (NAFLD) - Identification of Fibrosis-Promoting Factors in NAFLD

471 patients were enrolled. factors associated with LSM progression were steatosis grade 3 and albumin-bilirubin grade 2 or 3. the only factor associated with LSM regression was the rate of decrease in MRI-PDFF. LSM stage 0 (<2.5 kPa) In patients, adiposity grade 3 correlated with a higher incidence of LSM progression than adiposity grade 1 (MRI-PDFF < 11.3%), and in patients with LSM 1 or 2-4, an annual decrease in MRI-PDFF of 5% or more than 5% of the correlated with a higher incidence of LSM regression.