NCT00319189已完成4 期
Efficacy and Safety of Nateglinide Treatment in Renal Treatment Recipients With Post Transplant Diabetes Mellitus or Impaired Glucose Tolerance
University of Oslo School of Pharmacy2 个研究点 分布在 1 个国家目标入组 15 人开始时间: 2002年11月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 15
- 试验地点
- 2
- 主要终点
- Glucose tolerance
研究概览
简要总结
The objective of the present study is to evaluate both the efficacy and safet of nateglinide in renal transplanta recipients with posttransplant diabetes mellitus or impaired glucose tolerance. Primarily will the change in glucose tolerance and acute insuline responce be addressed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Reduced glucose tolerance (fasting glucose < 6.1 mmol/L AND 2 hour glucose between 6.7 and 9.9 mmol/L) or posttransplant diabetes mellitus (fasting glucose > 6.1 mmol/L OR 2 hour glucose between >= 10.0 mmol/L)
- •Stable patients fgollowing renal transplantation, less than 25% variation in serum creatinine last week and serum creatinine < 200 micromol/L
排除标准
- •Patients with indulin dependent diabetes mellitus before or after transplantation
- •Planned change in daily prednisolone dose during the study period
- •Haemoglobin < 8g/dL
结局指标
主要结局
Glucose tolerance
Insuline release
次要结局
- Glucose oxidation
- Postprandial hyperlipidemia
- Glomerular filtration rate
- HbA1C
- Fasting glucose
- Plasma nitric oxide
- Plasma endothelin-1
研究者
研究点 (2)
Loading locations...
相似试验
已完成
2 期
Nateglinide: a Double Blind Add-on Study With Pioglitazone for Type 2 Diabetic PatientsDiabetes Mellitus, Type IIType 2 Diabetes MellitusNCT00189774Astellas Pharma Inc
已完成
3 期
Double-Blind Comparison Between Mitiglinide and Nateglinide in Type 2 Diabetic PatientsDiabetesNCT00461617Kissei Pharmaceutical Co., Ltd.291
已完成
4 期
Efficacy and Safety of Naftopidil in Patient With Neurogenic Lower Urinary Tract Dysfunction Not Caused by Benign Prostatic HyperplasiaNeurogenic Lower Urinary Tract DysfunctionNCT02034604Samsung Medical Center194
Unknown
3 期
Relenvatinib in the Tatment of Recurrence of Hepatocellular Carcinoma After Liver TransplantationLiver TransplantationHepatocellular CarcinomaNCT04237740RenJi Hospital40
已完成
2 期
Natural Gels for Treatment of Plaque PsoriasisParapsoriasisNCT02330237Secret of Youth45