Effectiveness of Different Candies Against Bad Breath
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 35
- 试验地点
- 2
- 主要终点
- Organoleptic analysis of breathing air sample
研究概览
简要总结
This study is to analyze whether the candies can relieve or eliminate bad breath, both subjectively and objectively.
详细描述
This study is to systematically examine an existing candy, which is easily available and is intended to relieve or eliminate bad breath. The main aim of the study is to determine the effectiveness of the candies on the subjective perception of bad breath. The secondary outcome of the study is to investigate whether there is actually a decrease in volatile sulphur compounds (VSC) in the exhaled air and also a decrease in bad breath during organoleptic measurement.
The purpose of the study is to investigate whether the different candies can relieve or eliminate bad breath, both subjectively and objectively.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Non- smoker
- •No general medical illness or medication
排除标准
- •Allergies/intolerances to ingredients of the products used
- •Chronic diseases
- •Pregnancy
结局指标
主要结局
Organoleptic analysis of breathing air sample
时间窗: max 60 minutes at 3 different days
Assessment of the patient's bad breath on the basis of the subjective assessment of an investigator (scale of 0 to 5 (0, no odor; 1, questionable odor; 2, slight malodor; 3, moderate malodor; 4, strong malodor; 5, severe malodor))
Measurement of volatile sulphur compounds (VSC) in ppb (parts per billion).
时间窗: max 60 minutes at 3 different days
Assessment of the patient's bad breath on the basis of the objective assessment by a sulfide monitor (HaliSens® AI Analytical Innovations GmbH, Moosbach, Germany)
次要结局
未报告次要终点