JPRN-jRCT2080221705未知2 期
Phase II clinical study of TY-51924 in patients with acute myocardial infarction - Proof of concept study
适应症
试验速览
- 阶段
- 2 期
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 <= 79age old（—）
- 性别
- All
入选标准
- •1) Admission to hospital within 6 hrs of the onset of symptoms
- •2) Chest pain lasting for >= 30 min
- •3) ST-segment elevation of >= 0.2 mV in 2 or more contiguous precordial leads (V1-V4) on standard 12-lead electrocardiogram
- •4) TIMI flow grade 0/1 in left anterior descending artery (LAD) on diagnostic coronary angiography (CAG)
- •5) Written informed consent
排除标准
- •1) Prior documented old myocardial infarction (MI) or a clinical history of definite MI
- •2) Left main trunk (LMT) stenosis >50%
- •3) Total occlusion of left circumflex artery (LCX) or right coronary artery (RCA)
- •4) Left bundle-branch block
- •5) Suspected acute aortic dissection
- •6) Cardiac arrest or cardiogenic shock
- •7) Thrombolytic therapy or coronary artery bypass grafting (CABG)
- •8) Hepatic and/or renal dysfunction
- •9) History of allergy or drug hypersensitivity
- •10) Pregnancy or nursing mothers or childbearing women
研究者
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