Comparison of Analgesic Efficacy of Dexamethasone as an Adjuvant in Supraclavicular Block With Intravenous Dexamethasone After Supraclavicular Block in Patients Undergoing Forearm Surgeries
试验速览
- 阶段
- 2 期
- 入组人数
- 60
- 主要终点
- Dexamethasone efficacy as an Adjuvant in Supraclavicular Block
研究概览
简要总结
The use of dexamethasone perineurally along with local anesthetic has been shown to improve the duration of analgesia .
详细描述
Acute postoperative pain can be effectively controlled with the use of peripheral nerve blocks. Use of additives further prolongs the duration of analgesia For upper limb surgeries below shoulder joint, the brachial plexus block using supraclavicular approach introduced by Kulenkampff has gained popularity. Supraclavicular approach to brachial plexus block is useful for procedures done at or below the level of elbow.
This technique involves the deposition of local anesthetic near the brachial plexus approached from immediately above the clavicle. Brachial plexus is formed by ventral rami of C5, C6, C7, C8, and T1 which forms the roots.These then continue distally to form trunks, divisions, cords,and branches Local anesthetics used alone in supraclavicular block provide analgesia for 4-8 h.
The use of dexamethasone perineurally along with local anesthetic has been shown to improve the duration of analgesia. Intravenous dexamethasone is also useful in attenuating the postoperative need for analgesics in different clinical settings even in the absence of any nerve blocks.
Hence, it is logical to compare the duration of analgesia with the use of dexamethasone in the setting of supraclavicular brachial plexus block, dexamethasone given either perineurally or intravenously.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients between 18 and 60 years of age
- •Both male and female gender
- •ASA physical status Classes I and II patients
- •Patients posted for upper limb surgery below shoulder.
排除标准
- •Patient refusal
- •Patients with bleeding disorders and those on anticoagulant therapy
- •History of allergy to local anesthetics
- •Infection at the site of block
- •Neuro deficit involving brachial plexus
- •Pregnant women
- •Patients with psychiatric behavior
- •ASA physical status Classes III and IV patients
研究组 & 干预措施
group received dexamethasone perineural
injection dexamethasone 0.05 mg/kg perineural.
干预措施: Dexamethasone injection (Drug)
group received dexamethasone intravenous
injection dexamethasone 0.05 mg/kg intravenously.
干预措施: Dexamethasone injection (Drug)
结局指标
主要结局
Dexamethasone efficacy as an Adjuvant in Supraclavicular Block
时间窗: 2 years
we will assess the efficacy of dexamethasone in supraclavicular anaethesia in terms of duration of analgesia and onset of motor and sensory block.
次要结局
未报告次要终点
研究者
Islam Mohamed Abdel Hamid Ali
Resident doctor
Assiut University
