Biological Observational Monocentric Study Aimed at Analyzing the Lymphocytic Infiltrate of Lung Tumors
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- LYMPHOCYTE ISOLATION
研究概览
简要总结
The study is configured as a monocentric observational transversal biological study.
The main objective of the study is the reconstruction of the molecular organization of tumors of the thoracic cavity, in particular non-small cell lung cancer (NSCLC).
The study involves the collection of clinical data and biological material (blood and tumor tissue) from 70 subjects diagnosed with thoracic tumors.
详细描述
Inclusion criteria:
The study population will include all patients with the following characteristics:
- Ability to provide informed consent
- Men and women over the age of 18 years old
- Patients candidates for surgical treatment diagnosed with thoracic tumors
The procedures to which the patient will undergo during the study follow the standard of clinical practice for the treatment of pathology.
Exclusion criteria:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Ability to provide informed consent;
- •Men and women over the age of 18;
- •Patients candidates for surgical treatment diagnosed with thoracic tumors
排除标准
- •Previous chemotherapy for any cancer within the last 6 months;
- •Pregnant and/or breastfeeding women;
- •Immunosuppressive state (states of immunosuppression or ongoing immunosuppressive/immunomodulatory treatments)
结局指标
主要结局
LYMPHOCYTE ISOLATION
时间窗: from enrollment in the study to surgery at 15 days
the collection of lymphocytes, and their sequencing and analysis of differentially expressed genes.
次要结局
- Lymphocyte gene expression(from surgery to processing within 48 hours)
研究者
Pierluigi Novellis
MD
Scientific Institute San Raffaele