NCT03075787Unknown不适用
Cardiovascular Variability and Heart Rate Response Associated With Obstructive Sleep Apnea
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Amplitude of heart rate response associated with obstructive sleep apneas
研究概览
简要总结
Obstructive sleep apnea is often associated with microarousals and a stimulation of the sympathetic nervous system. The knowledge of this autonomic activation may help understanding the increase of cardiac risk observed in elderly. The aim of the study is to evaluate the relationship between obstructive sleep apnea severity, age, gender and heart rate response associated with obstructive sleep apnea. Drug-free patients diagnosed with obstructive sleep apneas were included. Clinical data and 24-h polysomnography recordings were analyzed.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Restless legs syndrome patients
- •Hospital routine for sleep disorders breathing diagnosis
- •Apnea index > 0
排除标准
- •Narcolepsy-cataplexy
- •Sleep irregularities and sleep deprivation symptoms
- •Lack of neurological or psychiatric diseases
- •Periodic leg movements
- •Central sleep apnea, treatment
- •Cerebral lesion
- •Medical illness
- •Medication or drinks affecting sleep and wake state.
结局指标
主要结局
Amplitude of heart rate response associated with obstructive sleep apneas
时间窗: At diagnosis
standard 24-h ambulatory ad libitum polysomnography
次要结局
- Other Heart rate variability indices: Ptot(At diagnosis)
- Other Heart rate variability indices: very-low-frequency (VLF), low frequency (LF), low frequency normalized units (LFnu), high-frequency normalized units (HFnu)(At diagnosis)
- Other Heart rate variability indices: LF/HF(At diagnosis)
研究者
研究点 (1)
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