The Effect of Blood Flow Restriction With and Without Arginine on Physical Performance and Growth Hormone
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Strength
研究概览
简要总结
The current study will investigate the effects of Blood Flow Restriction (BFR) training and L-arginine supplementation on recreationally trained female participants. In particular, it will compare performance outcomes and blood markers among two intervention groups (BFR and BFR+Arg) and a control group (CON).
详细描述
The current study will investigate the effects of Blood Flow Restriction (BFR) training and L-arginine supplementation on recreationally trained female participants. In particular, it will compare performance outcomes and blood markers among two intervention groups (BFR and BFR+Arg) and a control group (CON). All group will participate in the same training regimen. The control group will train and ingest a placebo pill. The BFR group will train with BFR and ingest a placebo pill, and the BFR+Arg group will train with BFR and ingest an L-arginine pill. All placebo pills will be Maltodextrin. The performance outcome is leg press 1RM, while the blood markers are growth hormone (GH) and cortisol. This analysis will provide insight as to whether or not L-arginine supplementation in addition to blood flow restriction training improves performance and muscle hypertrophy measure more than blood flow restriction training alone.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 25 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Signed informed consent
- •PAR-Q form complete and without contraindications
- •Body Mass Index (BMI) of 18.5-29.9 kg/m2
- •Stable body weight prior to participation in the study (fluctuation not exceeding 10 lbs. within the past 6 months
- •Agreement not to change current diet or exercise program (other than adding the program for the purpose of this study)
排除标准
- •Any diagnosed orthopedic condition that prevents exercise
- •BMI > 29.9 kg/m2 or < 18.5 kg/m2
- •Affirmative answer to any of the questions presented on the PAR-Q form
- •Are currently pregnant or planning to become pregnant during the study
- •Currently taking blood pressure medication
结局指标
主要结局
Strength
时间窗: Baseline measurements will be obtained during Week 0, then measurements will be taken at Week 4 and Week 8 to determine the amount of change in participant's strength at those particular time points compared to baseline
1 RM (rep-max) will be utilized to measure lower extremity strength
次要结局
- Growth Factor(Measured at Week 0, Week 4, and Week 8 at the following intervals: prior to supplement, 15 and 30 minutes post-supplementation (before exercise), and 90 minutes post-supplementation (after exercise))
研究者
Kristi Trammell
Assistant Professor, Doctor of Physical Therapy program
University of Mary Hardin-Baylor