Antithrombotic Strategies in Coronary Artery Dilatations and Aneurysms
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 51
- 试验地点
- 1
- 主要终点
- The nature of the antithrombotic treatment prescribed between the initial hospital discharge and the follow-up date
研究概览
简要总结
Objectives: The discovery of aneurysmal or ectatic lesions of the coronary arteries during coronary angiography or coronary CT angiography poses a triple challenge in terms of aetiology, treatment and prognosis. The aim of this study, based on coronary angiograms performed over a 10-year period at the Centre Hospitalier de Versailles, was to determine which antithrombotic treatment was routinely prescribed to patients with ACC or AEC, the evolution of this long-term treatment, and to analyse the association between the presence/absence of anticoagulant treatment and the rates of ischaemic cardiovascular events and haemorrhagic complications.
Materials and methods: This is a non-interventional, observational, single-centre study conducted at the Versailles Hospital Centre from 2013 to 2023, based on the department's coronary angiography registry. The study included adult patients, living or deceased, hospitalised in the cardiology department who underwent coronary angiography between 1 January 2013 and 31 December 2023, which showed the presence of aneurysms or ectatic atheroma with bi- or tri-vessel coronary involvement.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient > 18 years old
- •Patient living or deceased
- •Patient with aneurysmal or ectatic coronary artery disease with bi- or tri-truncular involvement at coronary angiography.
排除标准
- •Patient < 18 years old
- •Monotruncal aneurysmal or ectatic disease
- •Absence of coronary aneurysm / ectasia
- •Patient's opposition to participation in research
结局指标
主要结局
The nature of the antithrombotic treatment prescribed between the initial hospital discharge and the follow-up date
时间窗: Treatment on discharge from hospital and follow-up treatment beween 2013 and 2023
The nature of the antithrombotic treatment prescribed between the initial hospital discharge and the follow-up date (anti-platelet agents alone, single or dual therapy, anticoagulant alone, anti-platelet agent-anticoagulant combinations).
The nature of antithrombotic treatments
时间窗: Discharge from hospital (day 1)
The nature of antithrombotic treatments
次要结局
- The occurrence of ischaemic cardiovascular events (cardiovascular death, myocardial infarction, unscheduled coronary revascularisation)(The follow-up period between 2013 and 2023)
- The occurrence of haemorrhagic events of any kind(The follow-up period between 2013 and 2025)
研究者
Franck Assayag
hospital practitioner
Versailles Hospital