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临床试验/CTRI/2021/03/032132
CTRI/2021/03/032132尚未招募2 期

Correlation between thickness of gingival biotype and pH of gingival crevicular fluid in healthy subjects

Sri Hasanamba Dental College1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2021年3月20日最近更新:

试验速览

阶段
2 期
状态
尚未招募
入组人数
30
试验地点
1
主要终点
Correlation between thickness of gingiva and pH of crevicular fluid

研究概览

简要总结

Normally, there is a considerable intra-individual and inter-individual variation in both width and thickness of the facial gingiva, a fact that gives rise to the assumption that different gingival phenotypes might exist in any adult population. The bulky, slightly scalloped marginal gingiva with short and wide teeth on one hand and the thin, highly scalloped marginal gingiva with slender teeth on the other may serve to illustrate the existence of markedly different periodontal entities or so-called ‘‘gingival biotypes’’. The identification of the gingival biotype may be important in clinical practice since differences in gingival and osseous architecture have been shown to exhibit a significant impact on the outcome of restorative therapy. GCF plays a special part in maintaining the structure of junctional epithelium and the antimicrobial defense of periodontium. Understanding physical and chemical aspects of the gingival crevice microenvironment is essential for a comprehensive periodontal health evaluation. In this respect, gingival crevicular pH has been considered an indicator of periodontal health status and studied since 1954. It may play an important role in physiological and biochemical activities of the gingival crevice. In plaque-associated periodontal disease, crevicular pH is presumed to be influenced by changes in the microbial flora and proteinaceous metabolites, which produce inflammation in periodontal tissue. Many investigators have measured the crevicular pH and reported a relationship between pH and periodontal disease. This Randomized controlled clinical study aims to investigate the correlation between pH of gingival crevicular fluid and different types of gingival biotypes in healthy individuals.

研究设计

研究类型
Interventional
分配方式
Not Applicable
盲法
Not Applicable

入排标准

年龄范围
20.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • Systemically healthy subjects
  • Subjects having all maxillary anterior teeth
  • Subject’s age 20-70 years.

排除标准

  • Pregnant or lactating subjects
  • Subjects taking medication with any known effect on the periodontal soft tissues
  • Subjects with clinical signs of periodontal disease defined as having probing depth exceeding 3mm.
  • Subjects who are smokers.
  • Subjects with gingival hyperpigmentation.
  • Unable or not willing to comply with the study protocol.

结局指标

主要结局

Correlation between thickness of gingiva and pH of crevicular fluid

时间窗: 0th day

次要结局

  • Correlation between thickness of gingiva and pH of crevicular fluid(0th day)

研究者

申办方类型
Research institution and hospital

研究点 (1)

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