Interventions to Promote Brain Health Virtual Reality Study
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- MST memory performance
研究概览
简要总结
The Interventions for Brain Health Virtual Reality Study is a NIH-funded clinical research trial at the University of California San Diego (UCSD) Health under the supervision of the study principal investigator Dr. Judy Pa. The overarching goal of this trial is to use a novel virtual reality (VR) based intervention that simultaneously engages physical and cognitive activity aimed at improving brain health and cognition in older adults. The investigators will compare 3 types of interventions: physical activity, VR cognitive activity, and combined VR physical and cognitive activity over 16 weeks to evaluate physical and brain health changes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 50 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •50-85 years of age
- •Fluent in English
- •Can safely ride a stationary bike
排除标准
- •History of a neurological disorder
- •Severe sensory deficits
- •Inability to perform intervention (e.g., inability to cycle safely)
- •Contraindications to MRI scan (e.g., pacemaker)
- •Fear of needles/ blood
- •Prior history of fainting due to sight of needles of blood
研究组 & 干预措施
Cognitive activity - VR spatial navigation only
VR spatial navigation program will consist of a spatial navigation program that increases difficulty and length per trial over time. Spatial navigation is the ability to navigate between multiple elements/landmarks widely used in computer games. A trial is a test of performance or quality of someone or something.
干预措施: Cognitive Activity (VR) (Behavioral)
Combined, simultaneous physical and cognitive activity
The combined physical and cognitive activity VR program will consist of a spatial navigation program that increases difficulty and length per trial over time.
干预措施: Physical and Cognitive Activity (Behavioral)
Physical activity - Cycling only
The physical activity program will consist of a stationary bike cycling program. Each day will consist of a cycling program of varying levels of difficulty for 20-50 minutes.
干预措施: Physical Activity (Behavioral)
结局指标
主要结局
MST memory performance
时间窗: 16 Weeks
With the study's primary focus on hippocampal function, we will use the Mnemonic Separation Task (MST), a hippocampus-dependent discrimination test of similar objects, as our primary cognitive outcome. The MST is a memory task designed to heavily tax memory processes for making fine discriminations between highly similar objects or unrelated objects.
次要结局
未报告次要终点
研究者
Judy Pa
Co-Director of ADCS
University of California, San Diego