Reduced Nicotine Cigarette Purchasing Decisions
试验速览
- 阶段
- 早期 1 期
- 状态
- 已完成
- 入组人数
- 21
- 试验地点
- 1
- 主要终点
- Demand Intensity
研究概览
简要总结
The goal of this project is to experimentally evaluate how expectations about reduced-nicotine cigarettes as well as actual nicotine content interact to determine behavioral and subjective response for these novel products.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Reduced Nicotine Expectancy, Reduced Nicotine Dose
Receive reduced nicotine cigarette expecting reduced
干预措施: Reduced Nicotine Cigarettes (Drug)
Full Nicotine Expectancy, Reduced Nicotine Dose
Receive reduced nicotine cigarette expecting full
干预措施: Average Nicotine Expectancy (Behavioral)
Full Nicotine Expectancy, Full Nicotine Dose
Receive full nicotine cigarette expecting full
干预措施: Full Nicotine Cigarettes (Drug)
Full Nicotine Expectancy, Full Nicotine Dose
Receive full nicotine cigarette expecting full
干预措施: Average Nicotine Expectancy (Behavioral)
Reduced Nicotine Expectancy, Full Nicotine Dose
Receive full nicotine cigarette expecting reduced
干预措施: Full Nicotine Cigarettes (Drug)
Reduced Nicotine Expectancy, Full Nicotine Dose
Receive full nicotine cigarette expecting reduced
干预措施: Very Low Nicotine Expectancy (Behavioral)
Reduced Nicotine Expectancy, Reduced Nicotine Dose
Receive reduced nicotine cigarette expecting reduced
干预措施: Very Low Nicotine Expectancy (Behavioral)
Full Nicotine Expectancy, Reduced Nicotine Dose
Receive reduced nicotine cigarette expecting full
干预措施: Reduced Nicotine Cigarettes (Drug)
结局指标
主要结局
Demand Intensity
时间窗: Four times over approximately two weeks
Consumption of cigarettes at unconstrained price as measured by an incentivized demand task. Minimum value is 0, maximum value is not constrained. Higher scores indicate more cigarette consumption at unconstrained price (a worse outcome).
Demand Elasticity
时间窗: Four times over approximately two weeks
Changes in cigarette consumption with changes in price as measured by an incentivized demand task. There is no minimum or maximum value. Higher scores indicate greater cigarette price sensitivity (a better outcome). Values are log-transformed. Data are presented for all subjects with non-zero data (zero data cannot be analyzed with a demand function so elasticity cannot be generated)
次要结局
- Minnesota Nicotine Withdrawal Scale(Post-cigarette administration four times over approximately two weeks)