CTIS2023-508454-26-00进行中（未招募）1 期
Randomized Multi-center Clinical Trial to Assess Effectiveness and Safety ofTirofiban Versus Intravenous Aspirin in Patients With Acute Ischemic StrokeSecondary to Tandem Injury, Subject to Recanalization Therapy ThroughEndovascular Treatment - ATILA-ictus-2021
Fundacion Publica Andaluza Para La Gestion De La Investigacion En Salud De Sevilla0 个研究点目标入组 240 人开始时间: 2024年2月27日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 240
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 65+（—）
- 性别
- All
入选标准
- •Patients with acute ischemic stroke of the anterior territory secondary to a tandem lesion, with an indication for thrombectomy treatment according to the current recommendations of the Clinical Practice Guidelines, and the need for cervical stent placement., The intracranial occlusion locations that may be included are: carotid T, M1 and M2 segments of the middle cerebral artery, segment A1 of the anterior cerebral artery; and in the case that the posterior cerebral artery has fetal origin and is the site of intracranial occlusion., ASPECTS (Alberta Stroke Program Early computerized Tomography Score) =6., Greater than or equal to 18 years of age., Signed informed consent.
排除标准
- •Patients under 18 years of age., Pregnant., Patients with intracranial occlusive arteriosclerotic disease or extra or intracranial dissection., Documented allergy to acetylsalicylic acid or Tirofiban., Personal history of platelet penia (Platelets <100,000), Concomitant anticoagulant treatment (with presence of INR (International Normalized Ratio) > 1.7 in case of anti-vitamin K treatment or taking direct oral anticoagulant <48 hours ago), Medical history of the patient that carries a high risk of bleeding according to the investigator's criteria., Peptic ulcer active in the last 3 months., Patients with ASPECTS <6., Bilateral strokes or those produced by simultaneous occlusion of an artery in the anterior and posterior territory., Patients whose carotid stenosis is due to a re-stenosis or reocclusion of a pre-existing cervical stent., Candidate patients for carotid puncture., Previous treatment with double antiplatelet therapy for another cause prior to inclusion., Severe comorbidity and / or reduced life expectancy., Modified Rankin scale (mRS)> 2., Severe allergy to contrast medium.
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