NCT05545176招募中不适用
The Validation and Development of Termination-of-Resuscitation (TOR) Rules in Patients Following Out-of-Hospital Cardiac Arrest (OHCA) in Asia Countries
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 140,000
- 试验地点
- 1
- 主要终点
- survival to hospital discharge
研究概览
简要总结
Objectives/Hypotheses
- Prehospital termination-of-resuscitation (TOR) rules were developed in North American and European sites. Whether they remained valid in different geographic, ethnic, and cultural background areas is still under debate.
- Differences in characteristics of out-of-hospital cardiac arrests (OHCAs) and configurations of emergency medical service (EMS) between the Western and Asian countries, including relatively lower rate of presenting shockable rhythm (i.e. ventricular fibrillation / ventricular tachycardia; VF/VT), lower rates of bystander CPR, less advanced life support (ALS) implementation, and less public access defibrillators, might create potential threats to the prediction accuracy of TOR rules.
- We aim to conduct a study to validate the performance of ever published TOR rules in Asian OHCA population, including non-traumatic, traumatic, and pediatric OHCA patients. Furthermore, assess the possible variables that may impact the performance of TOR rules.
- We also aim to develop new TOR rules based on PAROS registry for Asia population, focusing on non-traumatic, traumatic, and pediatric OHCA patients, respectively.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •out of hospital cardiac arrest (OHCA) patients
排除标准
- •age <18 years
- •non-EMS transport to the emergency department
- •obvious signs of death (e.g. decapitation, rigor mortis, lividity, and decapitation) or having do-not-resuscitate (DNR) orders
- •missing data despite meeting the inclusion criteria.
研究组 & 干预措施
out of hospital cardiac arrest patients in Asia countries
干预措施: termination of resuscitation rules (Other)
结局指标
主要结局
survival to hospital discharge
时间窗: survival to 30-day hospitalisation
survival to 30-day hospitalisation
次要结局
- Cerebral Performance Categories Scale (CPC)(CPC within 30-day hospitalisation)
研究者
研究点 (1)
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