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临床试验/NCT05970913
NCT05970913进行中(未招募)不适用

The Value of PET-CT in Predicting Lymph Nodes Metastasis in Non Small Cell Lung Cancer

Fudan University1 个研究点 分布在 1 个国家目标入组 280 人开始时间: 2023年11月1日最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)
入组人数
280
试验地点
1
主要终点
Predictive value of 18F-FDG-PET/CT and 18F-FAPI-PET/CT for lymph node metastasis

研究概览

简要总结

This study is a single-center prospective clinical study that aims to evaluate the predictive value of preoperative 18F-FDG-PET-CT and 18F-FAPI-PET/CT for lymph node metastasis in patients with non-small cell lung cancer. The final pathological results were used to assess the predictive value of PET-CT for lymph node metastasis.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
20 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Solitary tumor, or multiple tumors with only ground-glass nodules (GGNs) apart from the primary lesion.
  • Diameter of the primary lesion ≤5cm, with a CTR between 0.5 and
  • Pathological confirmation of non-small cell lung cancer (NSCLC) either before or during surgery.
  • No prior radiotherapy or chemotherapy for initial treatment.
  • No history of malignant tumors.

排除标准

  • Locally advanced or distant metastasis.
  • Pleural dissemination observed during surgery.
  • History of malignant tumors.
  • Received neoadjuvant therapy.
  • Histopathological examination reveals lung malignancies other than non-small cell lung cancer (NSCLC).

结局指标

主要结局

Predictive value of 18F-FDG-PET/CT and 18F-FAPI-PET/CT for lymph node metastasis

时间窗: from enrollment to 1 month after surgery

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Haiquan Chen

Chief of the MDT board of thoracic cancer

Fudan University

研究点 (1)

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