Monitoring Post-transplant Living Donor Liver Functions by Thromboelastometry. A Prospective Observational Study.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- r (correlation coefficient) between clot firmness time at 20 minutes, clotting time and INR
研究概览
简要总结
A prospective Observational study including 50 living donor liver transplant recipients to monitor the graft functions through thromboelastometry
详细描述
This is a prospective observational study Includes 50 living donor liver transplant recipients performed in gastroenterology surgical center - Mansoura University liver transplantation program.
Study period: from June 2014 to May 2015 The early post-operative graft functions will be correlated with concomitant monitored thromboelastometric (TEM) parameters derived from a ROTEM Delt device
TEM Samples will be collected at the following times:
Pre-transplant 10 minutes post portal declamping at ICU admission Morning of Days from 1 to 7 Laboratory data relevant to graft functional status will be collected at the same times.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Living donor liver transplant recipients successively performed in the liver transplantation program - Mansoura university
排除标准
- 未提供
结局指标
主要结局
r (correlation coefficient) between clot firmness time at 20 minutes, clotting time and INR
时间窗: 20 minutes after starting the TEG test
Both blood sample for INR and other lab test and the sample for TEG will be simultaneously drawn from the arterial line for reading of days 0,1 and 2 then from the CVP for the rest of the study readings
次要结局
- r (correlation coefficient) between clotting time , clot firmness time at 20 minutes and serum bilirubin(20 minutes after the start of the TEG test)
- r (correlation coefficient) between clotting time , clot firmness time at 20 minutes and serum SGPT(20 minutes after the start of the TEG test)
研究者
Amr M. Yassen
Professor of Anesthesia and Intensive Care
Mansoura University