Comparison of Naproxen and Paracetamol for pain relief during endometrial biopsy in non-pregnant women with abnormal uterine bleeding; A randomized controlled trial

Panyananthaphikkhu Chonprathan Medical Center, Srinakharinwirot University0 个研究点目标入组 198 人开始时间: 2023年2月22日最近更新: 2024年8月19日

适应症

试验速览

阶段: 4 期
状态: 尚未招募
发起方: Panyananthaphikkhu Chonprathan Medical Center, Srinakharinwirot University
入组人数: 198

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•1.)A non-pregnant woman who has abnormal bleeding from uterus, age between 30 - 70 years old, with one of following criteria
•a.Age >/= 45 years
•b.Age < 45 years with unopposed estrogen exposure or chronic anovulation
•c.Persistent abnormal uterine bleeding
•3.)Not an anti-platelet or anti-coagulant agents user
•4.)Adequate communication with Thai
•5.)Consented to join the trial

•1. A woman who has had Paracetamol or NSAIDs agents within 24 hours before
•2. A woman who has a history of allergy to NSAIDs or Paracetamol
•3. A woman who has any contraindications in Naproxen using, such as peptic ulcer, asthma, bleeding disorder, and impaired renal or hepatic function; GFR < 30mL/min/1.73m2
•4. A woman who has any contraindications in Paracetamol using, such as impaired liver function; AST >100 U/L or ALT > 100U/L), and alcoholism.
•5. A woman who cannot understand the Visual Analogue Scale (VAS)
•6. Participants who need to withdraw from the trial.

发起方