跳至主要内容
临床试验/CTRI/2025/11/097498
CTRI/2025/11/097498尚未招募不适用

Temporal Summation in asymptomatic individuals with a history of low back pain

Manipal College of Health Professions MCHP1 个研究点 分布在 1 个国家目标入组 159 人开始时间: 2026年11月11日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
159
试验地点
1
主要终点
To investigate the variation in temporal summation of pain in asymptomatic individuals with a history of low back pain.

研究概览

简要总结

According to recent research, young Indian individuals are more likely than their Western counterparts to experience low back pain (LBP). Low back pain develops and persists due to both psychological and physical factors. Psychological factors can intensify or prolong pain experiences, such as fear-avoidance attitudes, which cause people to avoid movement or activity out of fear of pain. The processing and maintenance of pain are significantly influenced by physiological processes such as Central Sensitization, in which the nervous system becomes more sensitive to pain, and altered pain modulation.

The fact that not all healthy individuals exhibit temporal summation (TS) of pain—a condition in which repeated stimulation heightens pain perception—is another important observation. This variation occurs irrespective of the stimulus type. where it is administered on the body or how long it lasts. This implies that there can be significant differences in how each person processes pain, which could affect how pain is experienced as well as how well remedies work.

Knowing how temporal summation varies after LBP goes away may help explain why some people are more likely to experience pain episodes again. Certain pain processing patterns may be the focus of prevention or intervention if they continue to exist even after symptoms have subsided.

Additionally, researching temporal summation in individuals who are pain-free but have recovered from LBP may aid in the creation of individualized management plans. For those with a history of LBP, this tailored strategy may lower the chance of recurrent episodes and enhance long-term results.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 30.00 Year(s)(—)
性别
All

入选标准

  • Individuals with a history of low back pain within the last 2 years who have been asymptomatic for the last 3 months.

排除标准

  • Any ongoing pain • Spinal tumours • Infection • Trauma or fracture • Spinal deformities • Acute injury or recent spinal surgeries • Currently using pain medications such as opioids, analgesics, and sedatives.

结局指标

主要结局

To investigate the variation in temporal summation of pain in asymptomatic individuals with a history of low back pain.

时间窗: One time point

次要结局

  • To examine the relationship between fear-avoidance beliefs & temporal summation in individuals with a history of low back pain.(One time point)

研究者

发起方
Manipal College of Health Professions MCHP
申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Kaanchi Patel

Manipal College of Health Professions

研究点 (1)

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