跳至主要内容
临床试验/PACTR202007730554581
PACTR202007730554581已完成4 期

Characterization of muscle fatigue, rehabilitation and quality of life in a population with breast cancer.

APERE0 个研究点目标入组 39 人开始时间: 2020年5月26日最近更新:
适应症

试验速览

阶段
4 期
状态
已完成
发起方
入组人数
39

研究概览

简要总结

Compared to controls, a significant increase in the WS (P < 0.01) and the WD (P < 0.01) accompanied by a significant decrease in resting rHR (P < 0.01), exercising HR6' (P < 0.01), [La]b (P < 0.05), HR6'/WS (P < 0.01) and [La]b/WS ratios (P < 0.01) was reported in the trained group. However, a significant decrease both in WD (P < 0.01) and WS (P < 0.01) has been observed in the controls. No significant difference was observed in resting HR, exercising HR6', [La]b, HR6'/WS, and [La]b/WS ratios were observed in the control group. A significant improvement was observed for RPE in training group (P < 0.05).

研究设计

研究类型
Interventional

入排标准

年龄范围
19 Year(s) 至 44 Year(s)(—)
性别
Female

入选标准

  • Women aged from 18 to 65 years.
  • - No known history of chronic respiratory, cardiac or neuromuscular disease.
  • - Diagnosed with non-metastatic breast cancer (stage y–IIIA).
  • - Women who have had a mastectomy and are in the process of adjuvant chemotherapy (postoperative).

排除标准

  • - Hemoglobin concentration < 8 g/dL, platelet count < 20/nL.
  • - Obesity [body mass index (BMI) > 30].
  • - Malnutrition (BMI < 20).
  • - Treatment with high-dose corticoids (prednisone > 50 mg/day or equivalent dose of related agents).
  • - Chronic infection, neurological or muscular impairment.
  • - chronic diseases that could be exacerbated by exercise (coronary artery disease, chronic obstructive pulmonary
  • disease, osteoarthritis), skeletal metastases resulting in bone instability, or progressive disease

研究者

发起方
APERE

相似试验