A Retrospective, Observational, and Descriptive Study of Pediatric Cardiac Fibroma
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 17
- 试验地点
- 1
- 主要终点
- composite endpoint
研究概览
简要总结
This study was a retrospective descriptive case series analyzing outcomes of a novel surgical approach This study aimed to evaluate a modified surgical technique-called the Sandwich Procedure-for reconstructing the heart after resection of cardiac fibromas in children. Cardiac fibroma is a rare benign tumor that can compress vital cardiac structures and cause serious symptoms such as arrhythmia, heart failure, or obstruction of blood flow. Surgical removal is often required, but large tumors may leave defects in the heart wall that are challenging to repair, especially in young children.
The Sandwich Procedure was developed at our institution to improve the strength and stability of heart wall reconstruction after tumor removal. It involves suturing two layers of treated biological tissue-both inside and outside the heart wall-to restore normal shape and function, while minimizing the risk of complications like aneurysm or bleeding. This retrospective, observational study includes pediatric patients who underwent this procedure between 2018 and 2023. We report on its surgical feasibility, short- and mid-term outcomes, and potential benefits in preserving cardiac function.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 年龄范围
- — 至 14 Years(Child)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •underwent cardiac tumor resection
- •underwent ventricular reconstruction with the Sandwich Procedure
排除标准
- •the final pathological diagnosis indicated other than cardiac fibroma
- •the final pathological diagnosis indicated metastatic tumors
- •incomplete clinical or follow-up data
结局指标
主要结局
composite endpoint
时间窗: up to 5 years
all-cause mortality or cardiac reoperation
次要结局
- ventricular failure(up to 5 years)
- ventricular aneurysm(up to 5 years)
- malignant arrhythmia(up to 5 years)
- Heart block(up to 5 years)
- severe perioperative complications(before discharge)
