NCT07028710招募中不适用
Evolution of Luteal Progesteronemia in a Modified Natural Cycle (Ovulation Triggered by hCG): Pilot Study
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Serum Progesterone Level on Day 3 After hCG Trigger
研究概览
简要总结
This pilot study evaluates how progesterone levels change after hCG-triggered ovulation in modified natural cycles. Forty women preparing for frozen embryo transfer will have blood tests over 6 days to monitor hormone levels. The goal is to understand whether hCG affects the timing of the luteal phase and embryo implantation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •At least 1 follicle of 14 mm or more
- •Endometrium of 6 mm or more
- •Plasma luteinizing hormone (LH) less than 2 times basal level (measured at the beginning of the cycle between D1 and D4) and progesteronemia less than 1.5 ng/mL
- •For whom ovulation induction with recombinant hCG (Ovitrelle) is then proposed (standard care).
排除标准
- •Patient whose venous capital contraindicates repeated blood sampling over a short period of time over a short period.
- •Patient treated with exogenous natural progesterone (vaginal or injectable) which may interfere or synthetic progesterone, which may interfere with endogenous progesterone secretion.
- •Patient who has not given written consent to participate in the study.
- •Patient not fluent in French.
- •Patient under guardianship, curators or without social security coverage.
- •Patient participating in another study with an ongoing exclusion period or other interventional research with no ongoing exclusion period involves the use of a drug or procedure capable of altering progesterone levels .
研究组 & 干预措施
1
Experimental
干预措施: hCG (Drug)
结局指标
主要结局
Serum Progesterone Level on Day 3 After hCG Trigger
时间窗: 3 Days After hCG Injection
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
终止
4 期
Progesterone and Resting Energy ExpenditureWeight GainProgesteroneMenopauseNCT04140968Insel Gruppe AG, University Hospital Bern2
已完成
不适用
A Proof of Concept Study of Serum Progesterone Levels for IVF/ICSI Following HCG Trigger for Oocyte MaturationInfertility, FemalehCGIVFInfertilityNCT04417569ART Fertility Clinics LLC10
已完成
不适用
The Role of Progesterone and PIF for Successful Implantation and On-going Pregnancy in Assisted Reproductive TechnologyInfertilityNCT02129998Regionshospitalet Viborg, Skive873
已完成
4 期
The Luteal Phase After GnRHa Trigger - a Proof of Concept StudyProgesterone LevelsInfertilityNCT01504139Regionshospitalet Viborg, Skive93
尚未招募
不适用
Progesterone Primed Ovarian Stimulation Protocol Versus Antagonist Protocol for PCO PatientIVFPolycystic Ovary SyndromeInfertilityNCT05847660Fayoum University210