To compare the attenuation of hemodynamic response to pneumoperitoneum during laparoscopic cholecystectomy between lignocaine and dexmedetomidine
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 144
- 试验地点
- 1
- 主要终点
- to assess the efficacy of lignocaine & dexmedetomidine in altering hemodynamic response during pneumoperitoneum
研究概览
简要总结
Laryngoscopy ,endotracheal intubation, pneumoperitoneum, and extubation do lead tosignificant pressor response in patients undergoing laparoscopic cholecystectomy. Ourstudy is aimed at observing the attenuation of these sympathoadrenal responses usingdexmedetomidine and lignocaine hence providing intraoperative hemodynamicstability, better post operative pain control , minimal opioid consumption and it’s sideeffects, decreased duration of stay in hospital
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA 1-2 2)PATIENTS UNDERGOING ELECTIVE LAPAROSCOPIC CHOLECYSTECTOMY.
排除标准
- •PATIENT REFUSAL 2)ALLERGY TO LOCAL ANAESTHETIC AGENTS 3)PREGNANT AND LACTATING WOMEN.
结局指标
主要结局
to assess the efficacy of lignocaine & dexmedetomidine in altering hemodynamic response during pneumoperitoneum
时间窗: before induction , before pneumoperitoneum, every 5 minutes during pneumoperitoneum for 30 minutes then half hourly till deflation,after extubation ,in recovery room | postop 4 hrs,8 hrs,12 hrs, 24 hrs
次要结局
- comparing the time of request for first postoperative analgesia, sedation(ramsay sedation score immediate post op)