NCT04452786撤回不适用
Hormonal and Metabolic Aspects of Endoscopic Sleeve Gastroplasty
适应症
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 2
- 主要终点
- Changes in ghrelin (pg/ml)
研究概览
简要总结
The investigators of the study want to investigate the complex interactions between glucose metabolism, food intake/weight loss, and different appetite regulating hormones after ESG in comparison with conventional laparoscopic sleeve gastrectomy (LSG).
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age > 18 years
- •Scheduled for endoscopic or laparoscopic sleeve at Hvidovre Hospital
- •HbA1c < 48 mmol/mol before surgery, and no history of diabetes
- •HbA1c < 48 mmol/mol and fasting plasma glucose < 6.1 mmol/l at inclusion
排除标准
- •Hemoglobin < 6.5 mmol/l at inclusion
- •Pregnancy or breast feeding
- •Medication affecting the planned examinations
结局指标
主要结局
Changes in ghrelin (pg/ml)
时间窗: 240 minutes
Changes in ghrelin after a solid meal test compared before and after surgery
次要结局
- Changes in gut hormone response before and after sugery (pmol/L)(240 minutes)
研究者
Nora Elisabeth Hedbäck
Principal Investigator
Hvidovre University Hospital
研究点 (2)
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