NCT00387140已完成2 期
A Randomized Double-blind, Placebo-and Active Comparator-Controlled 2-Part Study to Evaluate the Efficacy of MK2295 in Patients With Postoperative Dental Pain
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 89
- 主要终点
- Peak analgesic response, safety, and tolerability
研究概览
简要总结
This study is being conducted to evaluate the safety and tolerability of the drug and to evaluate its efficacy compared to placebo and to ibuprofen in the treatment of postoperative dental pain in male patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Patients in generally good health who are scheduled to have two or more third molars removed, at least one of which is partially or completely embedded in bone and is a mandibular impaction
排除标准
- •Patient has a temperature of 37.5C or greater prior to dosing
- •Patient has participated in another clinical study within the last 4 weeks
结局指标
主要结局
Peak analgesic response, safety, and tolerability
时间窗: Over 24 Hours
次要结局
- Onset of analgesia, duration of analgesia(Over 24 Hours)
研究者
相似试验
已完成
1 期
Single and Multiple Ascending Oral Dose Study of RX-10001 in Healthy VolunteersHealthyNCT00941018Resolvyx Pharmaceuticals, Inc56
已完成
1 期
An Evaluation of VR942 in Healthy Volunteers and Patients With Mild AsthmaAsthmaNCT02473939Vectura Limited85
Unknown
1 期
Tolerability, Safety and Pharmacokinetic Study Of Mianhuahua Flavonoids Tablets in Healthy Adult SubjectsHealthyNCT02622230Xinjiang Uygur Pharmaceutical Co., Ltd.60
已完成
1 期
A Study to Evaluate LY3202328 in Overweight Healthy Participants and DyslipidemiaDyslipidemiasNCT02714569Eli Lilly and Company60
终止
1 期
Multiple Ascending Dose Study in Subjects With Type 2 DiabetesDiabetes MellitusNCT01856881Amgen86