A Prospective, Multi-Site, Interventional Case-Series Evaluating the MOVE (Movement-Oriented Velocity of Engagement) Protocol for Musculoskeletal Pain Recovery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 52
- 试验地点
- 8
- 主要终点
- Pain Reduction (NRS Score)
研究概览
简要总结
A Prospective, Multi-Site, Interventional Case-Series Evaluating the MOVE (Movement-Oriented Velocity of Engagement) Protocol for Musculoskeletal Pain Recovery
详细描述
The MOVE Protocol is a structured, biomechanics-based rehabilitation framework designed to accelerate recovery from musculoskeletal pain conditions through progressive mobilization and neuromuscular control. This interventional case-series involved multiple clinical and training centers (BodyGNTX, GFFI, IIKBS, ASFU) and applied standardized MOVE sessions under the supervision of certified movement specialists. Assessments included pain scoring (NRS), functional mobility (LEFS/UEFI), and balance control, measured at baseline, week 2, week 4, and week 8. The protocol followed ICH-GCP E6(R2) and Helsinki 2013 guidelines, with institutional ethics approval from MMSx Authority IREB. The study demonstrated safe and effective early-movement outcomes across diverse populations, emphasizing mobility, load optimization, and neuromuscular revalidation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
盲法说明
Open-label rehabilitation study. Both investigators and participants were aware of the intervention procedures, as exercise-based protocols require therapist supervision and participant engagement.
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •• Adults aged 18-65 years diagnosed with acute or subacute musculoskeletal pain or movement restriction (≤12 weeks duration).
- •Capable of performing supervised rehabilitation and daily movement tasks.
- •Able to provide informed consent and comply with study assessments.
- •Baseline pain score ≥4 on the Numerical Rating Scale (NRS).
排除标准
- •Chronic pain (>12 weeks) or neurological disorders affecting movement control.
- •Post-surgical cases or fractures within the past 3 months.
- •Cardiopulmonary or systemic illness contraindicating exercise participation.
- •Pregnancy or conditions limiting safe participation in physical rehabilitation.
- •Refusal to sign informed consent.
研究组 & 干预措施
Move Protocol
Participants received the MOVE (Movement-Oriented Velocity of Engagement) rehabilitation protocol, consisting of four progressive phases: Mobilize, Optimize Load, Validate Neural Control, and Energize Recovery. The program emphasized functional movement restoration, load tolerance, and neuromuscular coordination.
干预措施: MOVE Rehabilitation Protocol (Behavioral)
结局指标
主要结局
Pain Reduction (NRS Score)
时间窗: Baseline, Week 2, Week 4, and Week 8
Change in Numeric Rating Scale (NRS) for pain intensity from baseline to week 8 following the MOVE (Movement-Oriented Velocity of Engagement) rehabilitation program. Participants rated pain on a 0-10 scale where 0 = no pain and 10 = worst possible pain.
次要结局
- Functional Improvement (LEFS / UEFI Score)(Baseline, Week 2, Week 4, Week 8)
- Balance and Postural Stability (Timed Single-Leg Stance Test)(Baseline, Week 4, Week 8)
- Participant Perceived Recovery (Global Rating of Change Scale)(Week 8)