Correlation of apolipoprotien B and dyslipidemia with protienuria in type 2 diabetes mellitus patient.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 150
- 试验地点
- 1
研究概览
简要总结
Proteinuria is an early indicator of diabetic kidney damage in Type 2 Diabetes Mellitus. Apolipoprotein B (ApoB) is a key structural component of atherogenic lipoproteins, and many diabetic patients develop dyslipidemia, which may contribute to renal injury. This study explores how ApoB levels and patterns of dyslipidemia correlate with the presence and severity of proteinuria. Higher ApoB and abnormal lipid profiles (high LDL, high triglycerides, low HDL) are significantly associated with increased proteinuria. This suggests that ApoB may serve as a useful marker for early detection of diabetic nephropathy and highlights the importance of lipid control in preventing kidney complications in Type 2 diabete
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •patient with type 2 diabetes mellitus diagnosed with ADA 2025 guidelines.
排除标准
- •Age below 18 years.
- •Type 2 Diabetes Mellitus patients with concomitant diseases or conditions affecting the lipid levels such as-Hypothyroidism , Familial dyslipidemia, familial hypercholesterolemia, alcoholics to avoid false increase in apolipoproteins.
- •patient with Active liver disease patients on dialysis patients on lipid lowering drugs within 6 weeks and weight reducing diet pregnant and lactating female patients.
研究者
Dr Manish chandey
Sri Guru Ram das institute of medical sciences and research