Evaluate the Exposure to Toxicants Emitted During a Structural Fire Assessed by Urinary and Buccal Cell Biomarkers Found in Firefighters.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Studying biomarker levels in firefighters pre and post fire call.
研究概览
简要总结
Observational, within subject study design with 1 pre and 2 post-fire exposure biomarker samples collected to assess exposure to toxicants from combustion emissions related to fighting a structural fire.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Firefighter (career or volunteer)
- •Over 18 years of age
- •Able to provide written voluntary consent
排除标准
- •Unwilling to provide a pre and post-exposure urine sample
- •Current cancer diagnosis
- •Tobacco use within the last 1 year (verified by urinary TNEs)
研究组 & 干预措施
Firefighters over 18 years old
This is a within subject, observational study of firefighters. This study will involve three sample collections including buccal cells and urine samples; one collection pre and two collections post-structural fire exposure.
干预措施: Sample collection (Other)
结局指标
主要结局
Studying biomarker levels in firefighters pre and post fire call.
时间窗: 48 months
The investigators will evaluate the differences between mean pre-exposure biomarker levels and post-exposure levels in urine and buccal samples collected within 24 hours post-exposure and 1-week post-exposure respectively using t-tests to test for statistical significance.
次要结局
未报告次要终点