A Retrospective Study of the Effect of General Anesthesia on Children's Behavior
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 1,140
- 试验地点
- 1
- 主要终点
- Achenbach Child Behavior Checklist （CBCL）scale
研究概览
简要总结
This topic speculates that there is an interaction between family environment and anesthetic drug exposure on children's behavior. Different family environments have different response to anesthetic drug exposure. Children living in a specific family environment may be more susceptible to the effects of anesthetic drugs. People who are susceptible to exposure to narcotic drugs. In order to clarify this hypothesis and discover specific family environment factors that interact with anesthetic drug exposure, this project intends to establish a retrospective cohort study, through hierarchical analysis and other means, to clarify the behavioral changes of children in different family environments after exposure to anesthetic drugs. Provide theoretical support for the safe application of clinical children's anesthetics.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 5 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children aged 0-5 who underwent surgery at Shanghai Ninth People's Hospital
- •Current age is less than 18 years old
- •No surgical complications such as acute infectious diseases, systemic diseases
排除标准
- •History of neonatal hypoxic ischemic encephalopathy and bilirubin encephalopathy
- •There are genetic diseases or chromosomal diseases, neurological diseases (including epilepsy, congenital diseases), or a history of head trauma, a history of central nervous system infectious diseases, high fever convulsions, congenital heart disease, tumor diseases, and Patients with blood diseases
- •People who have autism, attention deficit hyperactivity disorder, or have received behavioral related treatments and interventions
- •Those who have undergone cardiovascular surgery, neurosurgery, or those with unstable hemodynamics during surgery
- •Those who cannot be contacted, refused to join the group, the questionnaire information does not match the medical records, or the complete medical records cannot be obtained
结局指标
主要结局
Achenbach Child Behavior Checklist （CBCL）scale
时间窗: immediately after the procedure
sorce（0-100），higher scores mean a worse
次要结局
未报告次要终点