Prediction of Optimal Pediatric Endotracheal Tube Size "Aged Based Formula Versus Ultrasonography"
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 54
- 主要终点
- Number of reintubation due to large or small tube (number and percentage %).
研究概览
简要总结
Background: Ultrasound (US) imaging technique has recently emerged as a novel, simple, portable, noninvasive tool helpful for airway assessment and management. Initial few published reports were on soft tissue imaging of neck, focusing on pre-tracheal structure and anterior tracheal wall. In our study, we compared the measurement of subglottic diameter using ultrasonography and the aged based formula in prediction of endotracheal tube size in children underwent elective surgical operation under general anesthesia.
Methods: Patients were randomly divided in 2 groups (27 patients each) using a computer-generated randomization schedule. The first group was aged based group (group AB) (n = 27): the endotracheal tube size was determined according to age of the child [inner diameter [ID] in mm = (age in yr/4) +4. The second group was ultrasound based group (group UB) (n = 27): the endotracheal tube size was determined according to the subglottic transverse diameter that was estimated with ultrasonography (the outer diameter of endotracheal tube (ETT OD) = 0.55*(subglottic diameter)+1.16) .
详细描述
Introduction:
Pediatric tracheal intubation requires considerable expertise and can represent a challenge to many anesthesiologists(Marciniak et al.,2009). Anatomically; the larynx of a pediatric patient assumes a funnel shape with its narrowest part at the level of the cricoid ring, which cannot be seen during conventional laryngoscopy (Karsli et al.,2002).
Choosing the correct endotracheal tube (ETT) size needed for intubation of pediatric patients is important because an inappropriately too large tracheal tube can cause upper airway damage (e.g., local ischemia, ulceration, scar formation) and the potential for subsequent subglottic stenosis. In contrast, an ETT that is too small may result in insufficient ventilation, poor reliability of end-tidal gas monitoring, leakage of anesthetic gases into the operating room environment, and an enhanced risk of aspiration(Karsli et al.,2002).
Different algorithms and formula have been proposed to choose the best-fitting size of the endotracheal tube. Age-based formulas, such as those of Cole and Motoyama, have been used to estimate optimal ETT size for more than half a century (Motoyama,1990) and this formula is [inner diameter (ID) in mm = (age in yr/4) +4]. Predictive formulas for appropriate ETT size have also been based on patient weight and height as[ID in mm = 2 + height in cm/30] and [ID in mm = 2.44 + age in yr ×0.1 + height in cm ×0.02 + weight in kg ×0.016] and other formula as the width of the 5th fingernail is used for ID prediction of the ETT [ID in mm = maximum width of the 5th fingernail] (Shibasaki et al.,2010). However, these methods are not always suitable because the size of the airway varies considerably between patients.
Ultrasound guided is helpful for evaluate the subglottic transverse diameter which is safe , sample, painless and non invasive modality for prediction of proper endotracheal tube size (Jagadish G Sutagatti et al., 2017).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 1 Year 至 6 Years(Child)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •fifty four children aged from 1 to 6 years of either sex
- •scheduled for elective surgery not exceeded 90 minutes
- •underwent general anesthesia with uncuffed endotracheal tube.
排除标准
- •an anticipated difficult airway
- •any respiratory disease that might cause airway narrowing
- •pre-exiting laryngeal or tracheal pathology
- •any lesion that could cause airway deformity due to fibrosis or the presence of a neck anatomical pathologies that might have unpredictable effect on the ultrasound assessment of the airway
- •prolonged surgery more than 90 minutes .
研究组 & 干预措施
Aged based group (group AB) (n = 27)
ETT size was determined according to age
Ultrasound based group (group UB) (n = 27): ETT was determined
ETT was determined according to the subglottic transverse diameter that was estimated with ultrasonography.
干预措施: ultrasound guided (Other)
结局指标
主要结局
Number of reintubation due to large or small tube (number and percentage %).
时间窗: 1 year
1- Number of optimum tube selection was monitored in both group (group AB and group UB) (number and percentage %).
时间窗: 1 year
次要结局
- complication after extubation(1 year)
- Time of intubation (minutes).(1 year)
研究者
Nevert Adel
Principal Investigator
Mansoura University
