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临床试验/NCT02900261
NCT02900261已完成不适用

Comparison of Methods to Measure the Consumption of Sodium and Caffeine in Children

University of Lausanne Hospitals1 个研究点 分布在 1 个国家目标入组 101 人开始时间: 2016年9月28日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
101
试验地点
1
主要终点
Urinary sodium excretion

研究概览

简要总结

This study will compare different methods (24 hour urine collection, evening and morning spots, and questionnaires) to measure the consumption of sodium and cafeine in children and adolescents.

详细描述

Sodium consumption among adults is high in Switzerland, as in most parts of the world. It is expected to be high in children as well, but little is still known. 24 hour urine collection is the golden standard to assess sodium consumption. However, this method is logistically difficult, especially for children. Therefore, alternatives are needed. Urinary spots have been used as a proxy to estimate sodium excretion over 24 hour in adults, but not in children. This study will assess whether urinary spots can be used to estimate sodium consumption in children in comparison to 24 hour urine collections.

Caffeine consumption has risen in children over the past years, mainly before of the increase in consumption of soda drinks. A precise way to measure caffeine consumption is by assessing the concentration of caffeine and its metabolites in 24 hour urine samples. An alternative to 24 hour urine collection is using questionnaires, however this remains difficult due to the multiples food sources of caffeine. This study will compare caffeine consumption estimated by 24 hour urine collection and by a semi-quantitative food frequency questionnaire targeting caffeine containing products.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Cross Sectional

入排标准

年龄范围
6 Years 至 16 Years(Child)
性别
All
接受健康志愿者

入选标准

  • Between 6 and 16 years of age

排除标准

  • A sickness that affects the consumption and excretion of sodium and caffeine (for example, diabetes, cardiovascular or gastrointestinal problems, chronic kidney disease, renal insufficiency)
  • Taking medication that affects sodium excretion (for example, diuretics)
  • A intravenous perfusion during the urine collection
  • Insufficient knowledge of French to understand the instructions

结局指标

主要结局

Urinary sodium excretion

时间窗: Over a 2-day period

Measured in 24 hour urine and estimated from 3 different urinary spots

Urinary caffeine and related metabolites excretion

时间窗: Over a 2-day period

Measured in 24 hour urine and estimated by a semi-quantitative food frequency questionnaire

次要结局

  • Urinary phosphate excretion(Over a 2-day period)
  • Sodium consumption(Over a 2-day period)
  • Urinary caffeine and metabolites excretion(Over a 2-day period)
  • Urinary albumine excretion(Over a 2-day period)
  • Urinary protein excretion(Over a 2-day period)

研究者

发起方
University of Lausanne Hospitals
申办方类型
Other
责任方
Principal Investigator
主要研究者

Arnaud Chiolero

Epidemiologist & Senior lecturer

University of Lausanne Hospitals

研究点 (1)

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