Comparison of Methods to Measure the Consumption of Sodium and Caffeine in Children
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 101
- 试验地点
- 1
- 主要终点
- Urinary sodium excretion
研究概览
简要总结
This study will compare different methods (24 hour urine collection, evening and morning spots, and questionnaires) to measure the consumption of sodium and cafeine in children and adolescents.
详细描述
Sodium consumption among adults is high in Switzerland, as in most parts of the world. It is expected to be high in children as well, but little is still known. 24 hour urine collection is the golden standard to assess sodium consumption. However, this method is logistically difficult, especially for children. Therefore, alternatives are needed. Urinary spots have been used as a proxy to estimate sodium excretion over 24 hour in adults, but not in children. This study will assess whether urinary spots can be used to estimate sodium consumption in children in comparison to 24 hour urine collections.
Caffeine consumption has risen in children over the past years, mainly before of the increase in consumption of soda drinks. A precise way to measure caffeine consumption is by assessing the concentration of caffeine and its metabolites in 24 hour urine samples. An alternative to 24 hour urine collection is using questionnaires, however this remains difficult due to the multiples food sources of caffeine. This study will compare caffeine consumption estimated by 24 hour urine collection and by a semi-quantitative food frequency questionnaire targeting caffeine containing products.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 6 Years 至 16 Years(Child)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Between 6 and 16 years of age
排除标准
- •A sickness that affects the consumption and excretion of sodium and caffeine (for example, diabetes, cardiovascular or gastrointestinal problems, chronic kidney disease, renal insufficiency)
- •Taking medication that affects sodium excretion (for example, diuretics)
- •A intravenous perfusion during the urine collection
- •Insufficient knowledge of French to understand the instructions
结局指标
主要结局
Urinary sodium excretion
时间窗: Over a 2-day period
Measured in 24 hour urine and estimated from 3 different urinary spots
Urinary caffeine and related metabolites excretion
时间窗: Over a 2-day period
Measured in 24 hour urine and estimated by a semi-quantitative food frequency questionnaire
次要结局
- Urinary phosphate excretion(Over a 2-day period)
- Sodium consumption(Over a 2-day period)
- Urinary caffeine and metabolites excretion(Over a 2-day period)
- Urinary albumine excretion(Over a 2-day period)
- Urinary protein excretion(Over a 2-day period)
研究者
Arnaud Chiolero
Epidemiologist & Senior lecturer
University of Lausanne Hospitals
