NCT00000449已完成4 期
Coping, Exposure, and Naltrexone Treatment With Alcoholics
National Institute on Alcohol Abuse and Alcoholism (NIAAA)2 个研究点 分布在 1 个国家目标入组 160 人开始时间: 1999年11月3日最近更新:
适应症
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 160
- 试验地点
- 2
研究概览
简要总结
The study's purpose is to improve alcoholism treatment by investigating the combined effectiveness of a psychotherapy (Coping Skills Training and Cue Exposure Treatment - CSTCET) with naltrexone in a randomized clinical trial. Individuals will receive 2 weeks of CSTCET or a control treatment as inpatients followed by 12 consecutive weeks of receiving either naltrexone or placebo as outpatients. Followups at 24, 48, and 72 weeks after treatment is completed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Treatment
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Meets criteria for alcohol dependence.
排除标准
- •Current diagnosis of dependence on other substances except nicotine.
- •A history of psychosis or current psychotic symptoms.
- •Current suicidality, homocidality, or psychiatric symptoms that require additional medication.
- •Current use of disulfiram (Antabuse).
- •Evidence of significant cerebral, renal, thyroid, or cardiac disease.
- •History of opioid abuse in the previous year.
- •History of cirrhosis, hepatocellular disease, or elevated bilirubin.
- •Females who are pregnant, nursing, or not using a reliable method of birth control.
研究者
研究点 (2)
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