Fractional FLOw Reserve In Cardiovascular DiseAses
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 64,045
- 试验地点
- 1
- 主要终点
- All-cause mortality
研究概览
简要总结
The FLORIDA (Fractional FLOw Reserve In cardiovascular DiseAses) study sought to investigate outcomes of FFR-guided versus angiography-guided treatment strategies in a large, real-world cohort.
详细描述
The objective of the FLORIDA study was to investigate mortality outcomes of FFR-guided versus angiography-guided treatment strategies in a large, real-world patient cohort, including patients with different stages of coronary artery disease as well as patients with acute coronary syndrome (ACS). All patients were followed for a period of 3 years after the index date. The analysis period extended from the individual index date to the date of death or the end of the 3-year follow-up period. Patients were matched for sex, presence of acute coronary syndrome, age ± 5 years, and propensity scores estimated with logistic regression based on 72 variables , with each FFR patient matched to the closest angiography-only patient
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •At least one inpatient coronary angiography for suspected coronary artery disease between January 2014 and December 2015.
排除标准
- •Loss to follow-up of other reasons than death (i.e. change of insurance)
结局指标
主要结局
All-cause mortality
时间窗: 36 months
All patients were followed for a period of 3 years after the index date. The analysis period extended from the individual index date to the date of death or the end of the 3-year follow-up period. The primary endpoint was mortality at 3 years, prospectively assessed at a quarterly basis.
次要结局
- All-cause mortality(24 months)