Efficacy of Neuromuscular Blockade Before Facemask Ventilation in Inducing General Anesthesia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 114
- 试验地点
- 1
- 主要终点
- mean tidal volume
研究概览
简要总结
This study is conducted to evaluate the efficacy of simultaneous injection of propofol and rocuronium in inducing general anesthesia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients undergoing elective surgery requiring endotracheal intubation
- •ASA I, II, and III
- •above 20 years
排除标准
- •refuse to enroll
- •patients with risk of aspirating gastric contents
- •patients in whom NMBs are contraindicated
- •patients with predictors of difficult mask ventilation
研究组 & 干预措施
simultaneous administration of propofol and rocuronium
In this group, the investigator will administrate propofol (2ml/kg) and rocuronium (0.6mg/kg) simultaneously, and start facemask ventilation after patient loss consciousness to induce general anesthesia.
The investigator will measure the mean tidal volume (TV) applied during facemask ventilation for 1 minute.
干预措施: administration of propofol and rocuronium (Drug)
ordinal administration of propofol and rocuronium
In this group, the investigator will administrate propofol (2ml/kg) first, and follow injection of rocuronium (0.6mg/kg) after patient loss consciousness and confirming facemask ventilation.
The investigator will measure the mean tidal volume (TV) applied during facemask ventilation for 1 minute.
干预措施: administration of propofol and rocuronium (Drug)
结局指标
主要结局
mean tidal volume
时间窗: from starting facemask ventilation for 1 minute
mean tidal volume of facemask ventilation in 1 minute
次要结局
未报告次要终点
研究者
Jeong-Hwa Seo
Professor
Seoul National University Hospital