Implant Insertion in Defective Anterior Maxillary Ridge Augmented Using Mineralized Plasmatic Matrix Versus Autogenous Bone Graft
试验速览
- 阶段
- 不适用
- 入组人数
- 20
- 主要终点
- Patient Satisfaction regarding esthetic results , outcome will be measure using questionnaire.
研究概览
简要总结
Using growth factors obtained from patient's venous blood mixed with particulate autogenous bone the study compares bone gain by implant with gold standards.
详细描述
To study the effectiveness of MPM in ridge augmentation with implant insertion compared with autogenous bone graft.
-PICO-
Population (P): Patients with defective maxillary alveolar ridge requiring implant insertion.
Intervention (I): Ridge augmentation with MPM.
Comparator (C): Autogenous bone graft.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Medically free patients.
- •Evaluated bone height on CBCT to be (0-4 mm buccal bone dehiscence) and width (not less than 4.5 mm)
- •Patients with Anterior maxillary defective partially edentulous ridge.
- •Age between 18 and 40 years.
- •Both sexes.
- •Patients physically able to tolerate surgical and restorative procedures.
- •Patients with an opposing tooth to the pre-implant site.
- •Good oral hygiene.
- •Highly motivated patients.
排除标准
- •Patients allergic to local anesthetic agent.
- •Pregnant or lactating females.
- •Presence of any pathosis in the pre-implant site.
- •Presence of any mucosal disease.
- •Presence of parafunctional habits.
- •History of oral radiotherapy.
- •History of prolonged steroids use.
- •Psychological disorders.
研究组 & 干预措施
Autogenous bone graft (Gold Standard).
Patients with defective maxillary alveolar ridges requiring implant insertion will have Autogenous bone graft (Gold standard) and collagen membrane to be used for bone augmentation around exposed threads of inserted dental implants.
干预措施: Autogenous bone graft (gold standard). (Other)
MPM Augmentation.
Mineralized plasmatic matrix (MPM) to be used without collagen membrane to augment the defect in the maxillary bone and cover the exposed threads of the dental implants.
干预措施: Mineralized plasmatic matrix (MPM). (Other)
结局指标
主要结局
Patient Satisfaction regarding esthetic results , outcome will be measure using questionnaire.
时间窗: 5 months
次要结局
- Stability of dental implants , this will be measured using Ostell device in ISQ units.(5 months.)
研究者
Mahmoud Usama Mahmoud El Masry
Dentist at menistry of health
Cairo University