The Effect of Homemade Herbal Mouthwash Versus Chlorhexidine on Plaque Accumulation in Gingivitis. A Randomized Clinical Trial.
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 入组人数
- 12
- 主要终点
- plaque index (O'Leary et al., 1972)
研究概览
简要总结
Gingivitis is a very common oral disease that may progress to the more destructive periodontitis if not treated. As oral plaque is a key player in gingivitis, plaque control by professional scaling and oral hygiene measures represents the main line of treatment.
Among the oral hygiene measures, using chlorhexidine mouthwash is considered the gold standard in mouthwashes. However, due to its side effects, a safer and more acceptable mouthwash is needed. Therefore, this study proposes mouthwashes made of infusion of natural herbs as an alternative.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Plaque-induced gingivitis.
排除标准
- •Medically compromised.
- •History of medications.
- •Pregnant females.
- •Periapical involvement in teeth.
- •History of periodontal surgery.
- •If gingivitis was due to local factor.
研究组 & 干预措施
Chlorhexidine mouthwash
干预措施: Chlorhexidine 0,12% (Drug)
Herbal Homemade Mouthwash
干预措施: herbal Mouthwash (Drug)
结局指标
主要结局
plaque index (O'Leary et al., 1972)
时间窗: 7 days
Plaque accumulation is tested on teeth with a probe. Number of sites having plaque accumulation will be divided by the total number of dental sites to get percentage of plaque accumulation.
次要结局
- Bleeding on probing(7 days)
- Changes in clinical signs of inflammation (Armitage, 2004)(7 days)
- Bleeding on brushing(7 days)
- Patient's acceptance of the mouthwash(7 days)