Diode Laser Therapy As An Adjunct To Non-Surgical Management Of Chronic Periodontitis - A Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 主要终点
- Change in levels of P.gingivalis
研究概览
简要总结
Laser therapy has been proposed as a novel treatment option in controlling subgingival microorganisms. This randomized controlled clinical trial evaluates the effect of 980nm diode laser as an adjunct to scaling and root planing (SRP) in the management of chronic periodontitis (CP).
详细描述
Conventional mechanical debridement can achieve a temporary decrease in the subgingival levels of Pg along with other pathogens. However, mechanical therapy alone may fail to eliminate pathogenic bacterial niches in inaccessible areas like deep pockets, root concavities, furcation areas etc. In search of more efficient and less traumatic techniques to improve periodontal healing, researchers proposed the use of lasers in periodontal therapy.
The adjunctive use of lasers with conventional tools may facilitate treatment and have the potential to improve healing. The diode laser is highly absorbed in hemoglobin and other pigments and is excellent for use in soft tissue surgical procedures.Laser application in improving clinical outcome in periodontal therapy, needs to be further investigated with well designed clinical trials. The investigators attempted to evaluate the efficacy of diode laser as an adjunct to SRP in the management of CP by evaluating clinical parameters coupled with quantitative estimation of P.gingivalis using Real-time Polymerase chain reaction (RT-PCR) assay.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 30 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •40 systemically healthy subjects diagnosed with generalized moderate CP in the age group of 30 to 50 years.
- •Minimum of 20 teeth having atleast two non-adjacent sites per quadrant with probing pocket depth of ≥ 5mm and clinical attachment loss of 3- 4 mm
排除标准
- •Patients who had undergone periodontal therapy 6 months prior to the commencement of the study.
- •Subjects on antibiotics or immunosuppressants.
- •Chronic smokers, alcoholics, smokeless tobacco users.
- •Subjects with acute illnesses/acute intraoral lesions.
- •Pregnant women
- •Subjects who had undergone extensive restorative dental treatment.
结局指标
主要结局
Change in levels of P.gingivalis
时间窗: 14 weeks
Microbial profile was assessed using PCR at baseline, 4-6 weeks and 12-14 weeks post treatment in both the study groups.
次要结局
- Change in gingival index(14 weeks)
- Change in plaque index(14 weeks)
- Change in probing pocket depth(14 weeks)
- Change in clinical attachment level(14 weeks)
研究者
Veena H.R
Reader, Department of Periodontics
KLE Society's Institute of Dental Sciences