Prospective Longitudinal Clinical Study for the Evaluation of Peri-implant Tissue and Osseointegration After Rehabilitation With Osseointegrated Implants

Selection of Research Participants Patients treated in the Implant Dentistry specialization course at FO-UFF, who undergo implant dentistry planning and receive rehabilitative treatment with endosseous implants, will be invited to participate in the research, provided they meet the inclusion criteria.

• Inclusion Criteria: Completion of surgical-prosthetic planning by the Implant Dentistry Clinic team at UFF, including osseointegrated implants and prosthetic components manufactured by SIN Implant System (São Paulo, Brazil); agreement to sign the informed consent form and willingness to be monitored for a period of 5 years, following the previously established course clinic protocol; systemically healthy patients who do not use antiresorptive and antiangiogenic drugs; patients with a plaque index <20% (Ainamo & Bay 1975) and bleeding on probing <20% (Muhlemann & Son 1971) at the start of the study.
• Exclusion Criteria: Patients undergoing rehabilitation with implants from different systems and/or not performed at the UFF Implant Dentistry specialization clinic; patients unable to attend radiographic follow-up over 5 years; patients unable to respond to questions in clinical analysis and satisfaction survey forms; presence of systemic conditions preventing the surgical procedure for dental implant installation; presence of metabolic bone disorders; presence of untreated or uncontrolled chronic or aggressive periodontitis; pregnant or lactating women.

Based on these criteria, a total of 148 research participants will be included and followed for 72 months (6 years).

Installation of Osseointegrated Implants Research participants will undergo clinical and prosthetic planning (reverse planning), including clinical-tomographic examinations and complementary tests, such as biochemical blood analysis and, when necessary, surgical risk assessment, according to the UFF Implant Dentistry specialization course protocol. The surgical technique, type of implant installed, and selected prosthetic components will follow the manufacturer's recommendations (SIN Implant System, São Paulo, Brazil), always considering treatment options for optimal patient rehabilitation.

1.1. Clinical Evaluation The clinical evaluation will include detailed anamnesis, assessment of participant satisfaction, peri-implant clinical examination, and evaluation of prosthetic connections over 5 years (Appendix 2). Clinical data will be updated throughout the study evaluations (Table 1) to analyze possible changes in satisfaction or peri-implant tissue condition.