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临床试验/NCT07666607
NCT07666607已完成不适用

Pathological Mechanism Study of Aerobic Exercise Regulating Cold Stress-induced Hypertension Via the Thermosensitive Target-mediated Sympathetic Nerve Pathway

Wang Jingfeng1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2024年10月4日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
200
试验地点
1

研究概览

简要总结

This study focuses on the specificity of thermosensitive targets in populations with hypertension in cold regions, identifies core targets through transcriptome sequencing and clinical validation, and clarifies the regulatory mechanism of moderate-intensity aerobic exercise through a prospective cohort study, providing scientific basis for precise prevention and treatment of hypertension in cold regions and personalized exercise intervention.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
60 Years 至 69 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Same as the inclusion criteria for cold region hypertensive patients in the first stage; No regular moderate-intensity aerobic exercise in the past 3 months (≥3 times per week, ≥30 minutes per session); Exercise risk assessment is low to moderate risk (negative PAR-Q+ questionnaire); Voluntarily participate in this study and sign informed consent.

排除标准

  • Same as the exclusion criteria in the first stage; Complicated with exercise contraindications (such as severe coronary heart disease, uncontrolled arrhythmia, severe osteoarthropathy, etc.); Unable to complete 16-week follow-up.

研究者

发起方
Wang Jingfeng
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Wang Jingfeng

Ph.D.

Harbin Sport University

研究点 (1)

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