Improving Cardiac Secondary Prevention Through Personalized Biomarker Knowledge
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 200
- 试验地点
- 2
- 主要终点
- Exercise capacity based on cardiopulmonary exercise testing
研究概览
简要总结
The purpose of this study is to determine whether providing individuals with personalized information on cellular aging, including telomere length, will stimulate them to adhere to cardiac prevention strategies and improve exercise capacity.
详细描述
Individuals who have sustained a heart attack are at considerable risk for future cardiac events. A cardiac rehabilitation and exercise program can reduce this risk but it remains a challenge to adopt optimum lifestyle changes. We will determine whether providing individuals with information on leukocyte telomere length, will motivate them to improve their exercise performance. We will test whether professionally conveying this information will stimulate an individual to adhere to proven cardiac prevention strategies, looking at the extent to which one's exercise capacity improves over time.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •1. Individuals who have sustained a myocardial infarction and entered the cardiac rehabilitation program
排除标准
- •Individuals with genetic mutations that affect telomere length
- •Individuals who may not have the mental capacity to understanding the ramifications of risk biomarkers
结局指标
主要结局
Exercise capacity based on cardiopulmonary exercise testing
时间窗: after 6-month cardiac rehabilitation program
Online VO2 maximum
次要结局
- Adherence to supervised exercise sessions(6 months)
- Activity assessment(6 months)
研究者
Geoffrey Pickering MD PhD
Professor
Western University, Canada