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临床试验/CTRI/2018/01/011166
CTRI/2018/01/011166尚未招募2/3 期

A CLINICAL STUDY ON AGNIKARMA AND JALAUKA AVACHARANA WITH ABHA GUGGULU IN MANAGEMENT OF SANDHIGATA VATA (OSTEOARTHRITIS OF KNEE JOINT)

All India Institute of Ayurveda1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2018年2月4日

试验速览

阶段
2/3 期
状态
尚未招募
入组人数
60
试验地点
1
主要终点
To evaluate the comparative clinical efficacy of Agnikarma and Jalauka Avacharana of

研究概览

简要总结

Osteoarthritis (OA) is predominantly a disease of the elderly but no age is exempted. It is caused by wear and tear of the joint. In OA, the top layer of cartilage breaks down and wears always. Worldwide OA is the most common joint disorder. OA is the commonest from of joints disease which is a painful and disabling in advancing years of life. Before 60 years of age 10 out of 100 and after 60 years 75 out of 100 persons suffers from OA of knee joints. After 60 years of age, this disease creates so much trouble that medical consultation becomes mandatory. Worldwide OA is the most common articular disease of people of 65 years and above.

In Ayurveda OA can be correlated with Sandhigata Vata. It is characterised by the symptoms of Shotha (swelling), Shula (pain), Vata Purna Driti Sparsha (palpable as an air filled bag) and Akunchana Prasarane Vedana (pain on flexion and extension of the joint), Hantisandhi (structural changes) and Atopa (crepitus).

In modern medicine various treatment options are available like conservative treatment, epidural steroid injection, radicular infiltration, surgical methods but all modalities have their own limitations and certain complications. In Ayurveda, Snehana, Upanaha, Agnikarma, Raktamokshana, Panchakarma, Bheshaja Chikitsa etc. have been recommended in the management of such manifestations. Among these Agnikarma and Raktamokshana have their own therapeutic values in the management of Sandhigata Vata. Jalauka avacharana is a kind of Raktamokshana, which has gained greater attention globally because of its medical values. It is also a procedure adviced in the management of OA.

Abha Guggulu is known for its Shothahara (anti-inflammatory), Shulahara (analgesic), Rasyana (Rejuvenative), Sandhankara (healing properties) actions. It is anticipated to be helpful in the treatment of OA. Though, it is being used in Ayurveda; but no comparative efficacy is available; considering which the current study is planned.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Open Label

入排标准

年龄范围
40.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • Patients suffering from Sandhigata Vata (Osteoarthritis of knee joint).

排除标准

  • Patients with Knee joint effusion, Known cases of secondary OA due to TB, Syphilis etc.; suffering with Diabetes mellitus, Severe anaemia, malignancy, bleeding disorders etc.

结局指标

主要结局

To evaluate the comparative clinical efficacy of Agnikarma and Jalauka Avacharana of

时间窗: 30 days

Management of Sandhigata Vata

时间窗: 30 days

次要结局

  • Improvement in quality of life(2 Months)

研究者

申办方类型
Research institution and hospital

研究点 (1)

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