The Effect of Deep Brain Stimulation on Movement-Related Cortical Potentials in Patients With Parkinson's Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- The primary measures are six EEG bereitschaftspotential areas and amplitudes.
研究概览
简要总结
The purpose of this study is to determine the effect of deep brain stimulation surgery on movement-related cortical potentials in patients with Parkinson's disease.
详细描述
Patients who have had deep brain stimulation surgery for Parkinson's disease at Mayo Clinic Arizona will have electroencephalographic (EEG) measurements with the stimulator on followed by EEG measurements with the stimulator off. Patients who are scheduled to have deep brain stimulation surgery for Parkinson's disease will have EEG measurements before and after surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 82 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who have had deep brain stimulation surgery for Parkinson's disease at Mayo Clinic Arizona, or who are scheduled to have deep brain stimulation surgery for Parkinson's disease at Mayo Clinic Arizona.
排除标准
- •Patients unable to do repetitive dorsiflexion of the wrist due to orthopedic problems.
- •Pregnant women.
- •Prisoners or institutionalized individuals.
研究组 & 干预措施
A
Ten patients who have had deep brain stimulation surgery for Parkinson's disease at Mayo Clinic Arizona.
干预措施: Deep brain stimulation surgery. (Procedure)
B
Ten patients who are scheduled to have deep brain stimulation surgery for Parkinson's disease at Mayo Clinic Arizona.
干预措施: Deep brain stimulation surgery. (Procedure)
结局指标
主要结局
The primary measures are six EEG bereitschaftspotential areas and amplitudes.
时间窗: 12 months
次要结局
- Unified Parkinson's disease rating scale score.(At time of EEG measurement.)
研究者
Virgilio Evidente
Professor of Neurology
Mayo Clinic